[AhrimanSefid]

I need a program to change the file structure or locking it or even encrypting it and the final result file be secure and no debugger or analyzer could read those files.
I wrote a program with Autoit which it's getting decompiled with exe2aut and I want to secure that.

[Deque]

no debugger or analyzer could read those files.

Not possible to that extend. You can only make it harder, not prevent analysing at all.

You can:
Use a good runtime crypter or build in crypting by yourself. Here it depends on the crypter's stub how hard it is to decompile or disassemble.
Use an obfuscator, which makes the code harder to read.
Use a language that compiles into a format that is harder to decompile (which means not .NET, not Java, not AutoIt, not Python, not Batch, but maybe C, C++).